Online Care in a Primary Care Setting

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Clopidrogel

Clopidrogel hydrogen sulfate/ Iscover Plax Plavix                                 preg risk B Indications: to reduce atherosclerotic events where there is MI, CVA or peripheral arterial disease.   Action: ANTIPLATELET inhibits platelet aggregation, by inhibition of binding of ADP to its platelet receptor.Irreversible modification of platelet, LASTS FOR LIFETIME OF PLATELET-lasts 5days, indicated for those intolerant to aspirin. Adverse : CNS: headache, dizziness, fatigue, depression, pain ENT: rhinitis, epistaxis GI: haemorrhage, abdo pain, dyspepsia, gastritis, constipation, diarrhea, ulcers GU: UTI Haematologic: purpura Musculoskeletal: arthralgia Respiratory: bronchitis, coughing, dyspnea, upper respiratory tract infection Skin : rash, pruritus Flu-like syndrome Contraindications ...
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Insulin

Insulin Classifications : exogenous Insulin Action: Is a hormone that promotes the storage of the body’s fuels 1.     Simulates the synthesis of glycogen from glucose (   glyconeogenesis ) 2.     Reacts with specific receptor sites to allow glucose into the cell –      Replaces endogenous insulin - Suppresses lipolysis – Glyco -neo-genesis:   The formation of glycogen from noncarbohydrates, such as protein or fat, by conversion of the latter to d-glucose.(medi lexicon) – Conversion of lipids into fat Various insulins available are processed within the body like endogenous insulin – Peak, onset and duration vary based on preparation Indications – Treatment of type 1 diabetes mellitus (IDDM) – Treatment of type 2 diabetes mellitus in people whose diabetes cannot be controlled by diet or other agents - treatment of type 2 diabetics who are stressed - managment of DKA, hyperkalaemia, and marked...
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Glibenclamide

Glibenclamide (Sufonylurea) Classifications : Sufonylurea- works only if pancreas has functioning beta cells. Adjunct to diet and exercise to lower blood glucose levels in type 2 DM Action:  Stimulate insulin release from the beta cells in the pancreas – They improve binding to insulin receptors -           Metabolized in liver and excreted in bile and urine Safer for those with renal disease. Adverse reactions : –Hypoglycaemia –GI distress : anorexia, nausea, vomiting, heartburn, diarrhoea –Allergic skin reactions   Contraindications : hypersensitivity, dka, diabetes complicated by fever, trauma, surgery ,renal or hepatic disease etc. Not for type 1 diabetics. Not for pregnancy. Care considerations : Learn to recognize signs of hypoglycaemia and hyperglycaemia to effectively manage condition. Drug-drug : – Drugs that acidifies the urine –Beta blockers –Alcohol 
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