Diphenhydramine (Benedryl)

Diphenhydramine (Benedryl)

class: Antihistamine ( expectorant) book p 829 says benedryl is guaifenesin

Actions : enhances output of respiratory tract fluids, reduces adhesiveness and surface tension of these fluids.-> more productive cough-> less coughing. Competitively blocks histamine at H1 receptors sites. Has atropine like antipruritic and sedative effects

Indications: symptomatic relief of respiratory conditions for a dry nonproductive cough in the presence of mucus in the respiratory tract.

Adverse: drowsiness and sedation. Dryness of respiratory and GI memebranes.Nausea, vomiting headache, dizziness, rash Drug – drug: moai, interacts fexofenadine, ketoconazole or erythromycin

Contraindications: diabetics (syrup of sugar)

Care/ Teaching: Administer on empty stomach, 1 hour before or 2 hours after meal, to increase absorption. May be given with meals if gi upset. lozenges to relieve dry mouth and GI upset., safety for falls, avoid alchohol,-> serious sedation. assess for allergies, persistent cough due to smoking, asthma or emphysema(not used in these cases)

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