Ipratropium (Atrovent)

Ipratropium (Atrovent)

class: anticholinergic

 Note: nasal spray, and inhaler

Indications: maintenance of bronchospasm associated with COPD, treatment of allergic rhinitis as nasal spray.

Actions: antagonizes the action of acetylcholine. Blocks vagally mediated reflexes. Dries up secretions caused by stimulation of PNS. Action is SLOW.  This is more of a preventer.

Adverse: Nervousness, dizziness, headache, nausea, GI distress, cough, palpitations.

Drug – drug: other anticholinergics. peanut allergies

Contraindications. Any condition aggravated by atropine like effects. Eg narrow angle glaucoma, bladder neck obstruction or prostatic hypertrophy, conditions aggravated by dry mouth and throat. The presence of known allergy to drug or soy products or peanuts( the vehicle used to make ipratropium int an aerosol contains a protein associated with peanut allergies)

 Drug : drug:other anticholinergics eg Atropine

              can be given with Ventolin(Salbutomol). they work together in to different ways.


Care/ Teaching: adequate hydration, encourage urination to avoid retention, small frequent meals, sugarless lozenges to relieve dry mouth and GI upset., no drive, review use of inhalator, no more than 12 inhalations in 24 hours

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