Tenecteplase

Tenecteplase(Metalyse)

Indications :Thrombolytic  -clot buster (ghost buster)



                                                                                    





Thrombolytic. Reduction of mortality

- Acute MI
–      Pulmonary emboli

–      Ischemic stroke

only available as an injectable. Monitored closely by attending physician.

Action: a human tissue plasminogen activator that binds to fibrin.

Adverse: uncontrollable bleeding,cardiac arrhythmias, hypersensitivity

Drug-drug: anticoagulants, drugs that alter platelet function(salycilates)

Contraindications: hypersensitivity, many others, monitored by physician

Care considerations: arrange to administer tenecteplase asap after MI. Timing is critical.

Discontinue heparin, monitor for blood loss(bruising, petechiae,bleeding gums, stools,urine). Use a medicalert. Monitor cardiac rhythm.

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