Oxycodone

Oxycodone/ OxyContin, Endone S8

Classification: Narcotic and opioid analgesic

Action: Binds with opiate receptors in CNS, altering perception and emotional response to pain.
            Mechanism unknown.

Adverse/Side Effects:
              CNS: sedation, somnolence, clouded sensorium, euphoria, dizziness, light-headedness.
              CV: hypotension, bradycardia.
              GI: nausea, vomiting, constipation, ileus.
               GU: urinary retention.
                Respiratory depression.
                Skin: sweating, pruritis
                Other: physical dependence.

Available Forms: Capsules, Oral suspension, Tablets, Tablets (SR), Injection, Solution for infusion,
                           suppositories.

Dose: 5mg PO q 6 hours, prn, or 10mg (SR) q 12 hrs.
          Suppository 1 , as required.

Contraindications: hypersensitivity, use within 14 days of MAO inhibitor therapy,
                          individuals with respiratory depression.

Drug to Drug interactions: Aminophylline, barbiturates, heparin, methicillin,
                               morphine sulfate, phenytoin, sodium bicarbonate, sulfonamide.

Care considerations;
            Use extreme caution in individuals with seizures, COPD, hepatic or renal disease,
                           acute abdominal conditions, hypothyroidism.
            Administer before person has severe pain.
            Administer with food or milk to minimise GI upset.
            Monitor circulation or respiratory status.
            Do not chew or crush tabs/capsules.

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